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Perfect for those with sensitive skin looking for a glow and a bit of an SPF boost. Highly recommend.

Vitamin C Serum

Vitamin C Serum

 (6525 Reviews)
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🧴Gentle & Sensitive Skin-Friendly

Formulated without common irritants like dyes, fragrance, masking fragrance, lanolin, parabens, and formaldehyde. Our minimalistic formula is trusted by dermatologists for even the most sensitive skin.

🍊Potent Vitamin C Complex

Features a stable 15% L-Ascorbic Acid (Vitamin C) combined with Ferulic Acid to help brighten skin, improve the appearance of fine lines, and protect against environmental damage.

💧Enhanced with Hydrating Hyaluronic Acid

Infused with Hyaluronic Acid to attract and retain moisture in the skin, helping to plump the appearance of fine lines and leave your complexion feeling smooth and supple.


🛡️Protects Skin Barrier Health

Works in harmony with your skin's natural barrier to provide antioxidant benefits without compromising its function, promoting resilient and healthy-looking skin.

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FORMULATED FOR SENSITIVE SKIN

The Most Important

Ingredient Is Trust™

Vanicream™ Vitamin C Serum is formulated without dyes, fragrance, masking fragrance, lanolin, parabens, and formaldehyde releasers. It is non-comedogenic (won't clog pores), non-greasy, and absorbs quickly. No botanical extracts or essential oils. pH balanced. Gluten-free. Dermatologist tested.

THD Ascorbate

Gentle & effective, ideal forsen sitive skin

Stable molecular structure that resists oxidation and yellowing

Not an acid, avoiding irritation for sensitive skin

Lipid-soluble for gentle, enhanced absorption

Gentle, potent Vitamin C without irritants.

The Vanicream Vitamin C Serum is a dermatologist-tested formula designed to be both effective and exceptionally gentle. It harnesses the power of a stable 15% L-Ascorbic Acid, the gold standard form of Vitamin C, to target visible signs of aging and environmental damage. True to the Vanicream promise, it is formulated without fragrances, dyes, parabens, and other known irritants, ensuring it supports your skin's health without compromise.

Glowing, protected, irritation-free skin.

Visibly Brighter Skin

Helps fade the appearance of post-acne marks and sun spots for a more even-toned complexion.

Powerful Protection

Provides a shield against environmental stressors and free radicals that cause premature aging.

Smoother Skin Texture

Works to reduce the look of fine lines and wrinkles.

Intense Hydration

Hyaluronic Acid draws in moisture to plump and soften the skin.

Ultimate Peace of Mind

Free of fragrances, dyes, and other common chemical irritants.

THD Ascorbate

Contains a potent yet gentle vitamin c derivative and ceramides

Absorbs quickly to enhance skin's brightness

Airless pump prevents .oxidation and color change

Potent, trusted Vitamin C

  • #1 Trusted Brand for Sensitive Skin: Formulated with the purity and safety you expect from Vanicream.
  • Potent 15% L-Ascorbic Acid: Features the most clinically proven form of Vitamin C for visible results.
  • Stabilized with Ferulic Acid: This key ingredient enhances the stability and efficacy of Vitamin C.
  • Dermatologist-Tested: Developed with and trusted by skincare experts.
  • Minimalist & Hypoallergenic Formula: Confidently made without: Fragrance, Dyes, Lanolin, Parabens, Formaldehyde.
  • Gentle & Dermatologist-Tested

    Formulated for sensitive skin and free of common irritants like fragrance, dyes, and parabens.

  • Potent 15% Vitamin C

    Features stable L-Ascorbic Acid to visibly brighten skin and reduce the appearance of fine lines and dark spots.

  • Hydrates & Protects

    Boosts moisture with Hyaluronic Acid and provides antioxidant protection against environmental damage.

    We Care About Your Skin

    The Most Important Ingredient Is Trust™

    You can be assured that we go to great lengths to select ingredients that are safe and effective, are suitable for our customers, and are tested and monitored for quality.

    About Vanicream

    Our Story

    From the founders Conrad Thompson and Ed Mansfield (2010)

    In 1974 we were both pharmacists working in a local hospital. Neither of us had any thoughts of starting a manufacturing company. However, at that time we worked closely with dermatologists and understood the needs of their patients. Because of our extensive experience formulating products, it was suggested by several dermatologists that we start a company to make better products than what were commercially available for people with sensitive skin. We investigated this idea and formed Pharmaceutical Specialties, Inc. (PSI) in 1975.

    We developed PSI while continuing to work full-time at the hospital. Space was rented in a small building and a few part-time assistants were employed. As word spread about our products, business increased and we moved several times to larger facilities to accommodate our growth. We both retired from the hospital in the mid ‘90s to manage PSI on a full-time basis. Brian Leary and Rick Sandwick joined Conrad Thompson and Ed Mansfield (co-founders) as partners in January 2005.

    Early on, we made decisions regarding our operating principles. We wanted to avoid chemicals that dermatologists considered undesirable and could be irritating or sensitizing to the skin, such as fragrance, masking fragrance, dyes, lanolin, parabens, and formaldehyde releasing preservatives. We wanted to use the highest quality ingredients that would conform to this principle. Even though most of our products were, and are, considered cosmetics by the FDA, we chose to manufacture to drug quality standards. This meant meeting or exceeding the FDA’s current Good Manufacturing Practice regulations. Our marketing focus would be to dermatologists and allergists and our distribution primarily through pharmacies, and later, selected medical supply providers. We wanted to provide high quality products at a competitive price which offer good value to consumers. In communicating with physicians and the public, we wanted to be conservative with claims and not use misleading and meaningless terms such as “hypo-allergenic” and “natural.”

    Initially, we distributed products mainly in the upper Midwest. Today we distribute throughout the USA and internationally.

    We are regularly inspected by the FDA and licensed by the Minnesota State Board of Pharmacy as a pharmaceutical manufacturer.

    Throughout the evolution of PSI, we have been extremely fortunate in obtaining and keeping employees who are dedicated, have great knowledge and skill, ambition, honesty, talent and loyalty. We consider the employees our “PSI family.”

    We are grateful for the support and loyalty we receive from physicians and pharmacists that recommend our products and the patients who benefit from them.

    It is our intention to continue to manufacture and develop new products in the same manner that we have in the past 35 years.

    Thank you for your interest in the products we manufacture.

    • ★★★★★

      Love this product

      My skin is pretty sensitive when it comes to vitamin c, but I LOVE this product. The consistency feels nice and hydrating and I have zero irritation using it both morning and night. Generated as part of the Vanicream™ Love Your Skin Care Contest.

      Chris

    • ★★★★★

      Very Nice!

      I have been using this for only a week so too soon to see a real difference. I use it in the AM as added moisture under the facial SPF moisturizer. I do think it has lightened my under eye area. No problem with using it on my rosacea skin:)

      Kathleen

    • ★★★★★

      Vitamin C Serum review

      I have been using the vitamin c serum from vanicream for a few years. It is light and layers perfectly under sunscreen. Vitamin c makes my skin glow and doesn’t cause breakouts! Generated as part of the Vanicream™ Love Your Skin Care Contest.

      Jennifer

    • ★★★★★

      Love this product!

      I was very skeptical at first, but after a month of using the product I’m absolutely in love with it and has become a daily use in my routine! I tell everyone I know that they need this product and not to waste so much money on expensive brands!

      Evaunielle

    • ★★★★★

      Best Vitamin C I've tried

      Most vitamin c serums break out my skin or give me eczema patches, but not this one. I like it because it's gentle and affordable. I started really noticing a difference in the brightness of my skin about 3 months into using it.

      Ana

    • ★★★★★

      Great for sensitive skin!

      I have very sensitive skin so it’s hard to find a serum that doesn’t break me out, this one doesn’t! I also apply to my under eyes as well and feel like they are lighter but not totally gone. I definitely reccomend it :)

      Angela

      Frequently Asked Questions

      What are the key ingredients in Vanicream™ Vitamin C Serum?

      Our Vitamin C Serum contains a potent yet gentle vitamin C derivative (tetrahexyldecyl ascorbate) and ceramides to enhance the skin’s brightness for a fresh glow.

      What is tetrahexyldecyl ascorbate?

      Tetrahexyldecyl Ascorbate (or THD-Ascorbate) is an effective yet gentle vitamin C derivative. The formula behind our Vanicream™ Vitamin C Serum was designed to provide the same benefits you would expect from other ascorbic acid products while minimizing sensitivity and irritation, making it ideal for individuals with sensitive skin.

      How will this serum benefit my skin?

      Our milky, lightweight serum absorbs quickly to enhance the skin’s brightness for a fresh glow.

      How is this serum packaged?

      We’ve packaged our Vitamin C Serum in an airless pump tube. This type of packaging helps prevent oxidation and color change, ensuring the serum lasts longer than many other Vitamin C  serums. This packaging is also ideal for travel, as it meets the TSA’s carry-on requirements.

      Where should this serum fit in with my skincare routine?

      This serum works best following a cleanser, but before applying any moisturizer, sunscreen, or makeup.

      How often should I use this Vitamin C serum?

      We recommend using our Vitamin C Serum once daily, as a part of your morning or nightly routine.

      Is the Vanicream™ Vitamin C Serum suitable for all skin types?

      We designed our Vitamin C Serum for sensitive skin, which is also ideal for dull or uneven skin types.